
Diabetes is a metabolic disorder characterized by chronic elevation of blood glucose levels (hyperglycemia) due to the body’s inability to produce sufficient insulin or to use it effectively. This condition primarily affects the metabolism of carbohydrates, fats, and proteins, and can lead to serious complications such as cardiovascular disease, kidney failure, neuropathy, and retinopathy. Classified into Type 1, Type 2, gestational, and other specific types, diabetes is now recognized as a majo
ENSevilay Yeşilyurt

Thrifty Gene Hypothesis is a biological model that attributes the susceptibility to obesity and type 2 diabetes in modern human populations to evolutionary adaptations. It was first introduced in 1962 by American geneticist James V. Neel to explain the evolutionary basis of diabetes.Layla Brassington vd., “Integrating the Thrifty Genotype and Evolutionary Mismatch Hypotheses to Understand Variation in Cardiometabolic Disease Risk,” Evolution, Medicine, and Public Health 12, no. 1 (2024): 214, er
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Emine Nur ERDEM