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Golden blood, known as the Rh-null phenotype, is one of the rarest conditions among human blood groups. This phenotype is defined by the complete absence of all antigens in the Rh system. Such comprehensive deficiency has been observed in only a very small number of individuals, making golden blood both clinically unique and scientifically invaluable. The term “golden” in popular usage stems from its rarity and its strategic importance in transfusion medicine. Rh System and Molecular Basis The R