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During the COVID-19 pandemic, virus has undergone mutations, producing various variants. Each of these variants has carried different mutations that affect the virus’s transmission speed and contagiousness. June The XEC variant, which emerged in 2024, is a hybrid of the KS.1.1 (FLiRT) and KP.3.3 (FLuQE) variants. Characteristics of the XEC Variant The XEC variant has several important mutations in the SARS-CoV-2 spike protein. The substitution of the glutamine amino acid with glutamic acid in th