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Staphylococcus aureus was first isolated and identified in 1880 by Scottish surgeon Sir Alexander Ogston from pus samples. The bacterium quickly gained clinical importance due to its frequent association with surgical wounds and purulent infections. With the widespread introduction of penicillin in the 1940s, it was believed that S. aureus infections could be brought under control, but penicillin resistance emerged rapidly. The appearance of methicillin-resistant strains (MRSA) in the 1960s reve