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Vibrio cholerae is a Gram-negative, comma-shaped, motile bacterium that causes cholera. It spreads via the fecal-oral route, primarily through contaminated water and food, and poses serious public health challenges under inadequate sanitation conditions. Naturally present in aquatic ecosystems, V. cholerae is notable for its environmental reservoirs and pathogenic properties. Microbiological Characteristics Morphology and Physiology Vibrio cholerae is a Gram-negative, comma-shaped bacterium belo